- Ep: 34
- On Infernal Ground
- Guest Starring: Will Tudor (Sebastian Verlac), David Castro (Raphael Santiago), Mimi Kuzyk (Imogen Herondale), Lola Flanery (Seelie Queen), Jade Hassouné (Meliorn), Alexandra Ordolis (Ollie), Anna Hopkins (Lilith), Tessa Mossey (Heidi McKenzie)
- Co-Starring: Natalie Moore (Stella), Randal Edwards (Tim), Sophia Walker (Catarina), Phillip MacKenzie (Brother Enoch), Troy James (Flying Demon), Eileen Li (Aline Penhallow), Brooks Darnell (Charlie), Gina Phillips (Young Professional), Brian Kaulback (Elderly Man)
- Written By: Todd Slavkin & Darren Swimmer
- Directed By: Matt Hastings
- Memorium: In Memory of Simon Jacques
- Ep: 35
- The Powers That Be
- Guest Starring: Javier Muñoz (Lorenzo Rey), Anna Hopkins (Lilith), Noah Danby (Russell), Ray Ablack (Raj)
- Co-Starring: Luke Gallo (Rufus), Sophia Walker (Catarina), Kevin Alves (Bat), Randall Edwards (Tim), Ariana Williams (Madzie), Robyn Alomar (Hostess), Sam Asante (Warlock), Brooks Darnell (Charlie), Michael Giel (Glenn), Doug MacLeod (Mr. Harris), Neeraja Ramjee (Disciple #1), Daniel Coz (Disciple #2)
- Written By: Peter Binswanger
- Directed By: Peter DeLuise
- Ep: 36
- What Lies Beneath
- Guest Starring: Will Tudor (Sebastian Verlac), David Castro (Raphael Santiago), Noah Danby (Russell), Anna Hopkins (Lilith), Alexandra Ordolis (Ollie), Nicola Correia-Damude (Maryse Lightwood), Tessa Mossey (Heidi McKenzie), Genevieve Kang (Morgan Young)
- Co-Starring: Brooks Darnell (Charlie), Rosalba Martinni (Rosa), Josh Horvath (ND Vampire)
- Written By: Alex Schemmer
- Directed By: Amanda Row
- Ep: 37
- Thy Soul Instructed
- Guest Starring: David Castro (Raphael Santiago), Anna Hopkins (Lilith), Chai Hansen (Jordan Kyle), Tessa Mossey (Heidi McKenzie), Steve Byers (Underhill), Genevieve Kang (Morgan Young)
- Co-Starring: Jesse Camacho (Leo), Jamaal Grant (Parking Patrolman), Alyssa Capriotti (Lindsay)
- Written By: Jamie Gorenberg
- Directed By: Emile Levisetti
- Ep: 38
- Stronger Than Heaven
- Guest Starring: Anna Hopkins (Lilith), Chai Hansen (Jordan Kyle), Lisa Berry (Sister Cleophas), Steve Byers (Underhill)
- Co-Starring: Brooks Darnell (Charlie), Benjamin Sutherland (Ithuriel), Daniel Coz (Disciple #3)
- Written By: Brian Millikin
- Directed By: Geoffrey Wing Shotz
- Ep: 39
- A Window Into an Empty Room
- Guest Starring: Anna Hopkins (Lilith), Chai Hansen (Jordan Kyle), Tessa Mossey (Heidi McKenzie), Alexandra Ordolis (Ollie), Steve Byers (Underhill), Nicola Correia-Damude (Maryse Lightwood)
- Co-Starring: Brooks Darnell (Charlie), Jonathan Ho (Brother Zachariah), Tazito Garcia (Praetor #1), Neion George (Guard)
- Written By: Aisha Porter-Christie
- Directed By: Alexis Ostrander
- Ep: 40
- Salt in the Wound
- Guest Starring: Mimi Kuzyk (Imogen Herondale), Anna Hopkins (Lilith), Chai Hansen (Jordan Kyle), Alexandra Ordolis (Ollie), Francoise Yip (Consul Jia Penhallow)
- Co-Starring: Sophia Walker (Catarina), Kevin Alves (Bat), Tara Joshi (Samantha), Roseline Mouana (Clave Guard)
- Written By: Celeste Vasquez
- Directed By: Joshua Butler
- Ep: 41
- A Heart of Darkness
- Guest Starring: Anna Hopkins (Lilith), Chai Hansen (Jordan Kyle), Nicola Correia-Damude (Maryse Lightwood), Alexandra Ordolis (Ollie), Lola Flanery (Seelie Queen), Francoise Yip (Consul Jia Penhallow)
- Co-Starring: Tomaso Sanelli (Young Jace), Leonidas Castrounis (Young Alec), Ana Maria Mallinos (Young Isabelle), Phillip MacKenzie (Brother Enoch)
- Written By: Jamie Gorenberg
- Directed By: Ari Sandel
- Ep: 42
- Familia Onte Omnia
- Guest Starring: Javier Muñoz (Lorenzo Rey), Anna Hopkins (Lilith), Chai Hansen (Jordan Kyle), Francoise Yip (Consul Jia Penhallow), Tessa Mossey (Heidi McKenzie), Alex Mallari, Jr. (Detective Greere), Noah Danby (Russell), Christina Cox (Elaine Lewis), Holly Deveaux (Rebecca Lewis)
- And: Alan Van Sprang (Valentine Morgenstern)
- Co-Starring: Sophia Walker (Catarina), Voytek Skrzeta (Brother Solomon), Christopher Tai (Charles Freeman), Bradley Hamilton (Trevor Hayes), Stephanie Belding (Iris Rouse), Rachelle Casseus (Detective Mendez)
- Written By: Taylor Mallory
- Directed By: Matt Hastings
- Ep: 43
- Erchomai
- Guest Starring: Anna Hopkins (Lilith), Jack Yang (Asmodeus), Alexandra Ordolis (Ollie), Nicola Correia-Damude (Maryse Lightwood), Christina Cox (Elaine Lewis), Holly Deveaux (Rebecca Lewis), Conrad Coates (Detective Dwyer)
- Co-Starring: Jacob Skiba (Young Jonathan), Neeraja Ramjee (Disciple #1), Daniel Coz (Disciple #2), Danielle Ayow (Admit Nurse), Samora Smallwood (Uniformed Officer), Luke Marty (Security Guard)
- Written By: Bryan Q. Miller
- Directed By: Jeffrey Hunt
- Ep: 44
- Lost Souls
- Guest Starring: David Castro (Raphael Santiago), Luke Baines (Jonathan Morgenstern), Francoise Yip (Jia Penhallow)
- Co-Starring: Stephanie Belding (Iris Rouse), Sophia Walker (Catarina), Ariana Williams (Madzie), Cassius Doroja (Young Magnus), Jason Gosbee (Seelie Warrior)
- Written By: Todd Slavkin & Darren Swimmer
- Directed By: Matt Hastings
- Ep: 45
- Original Sin
- Guest Starring: Luke Baines (Jonathan Morgenstern), Pasha Ebrahimi (Cain), Lola Flanery (Seelie Queen), Jade Hassouné (Meliorn)
- Co-Starring: Tom Rooney (Mirek), Charlie Morgan (French Shadowhunter)
- Written By: Alex Schemmer
- Directed By: Matt Hastings
- Ep: 46
- Beati Bellicosi
- Guest Starring: Chai Hansen (Jordan Kyle), Nicola Correia-Damude (Maryse Lightwood), Luke Baines (Jonathan Morgenstern), Tessa Mossey (Heidi McKenzie), Noah Danby (Russell), Romaine Waite (Griffin)
- Co-Starring: Kevin Alves (Bat Velasquez), Wole Daramola (Greenlaw), Seamus Patterson (Praetor Nick), Katie Strain (Nora), Josh Horvath (Joshua), Michael Brown (Praetor #1), Aimee Bessada (Elle)
- Written By: Brian Millikin
- Directed By: Michael Rohl
- Ep: 47
- A Kiss From a Rose
- Guest Starring: Javier Muñoz (Lorenzo Rey), Chai Hansen (Jordan Kyle), Luke Baines (Jonathan Morgenstern), Steve Byers (Underhill), Alex Mallari, Jr. (Detective Greere)
- Co-Starring: Rachelle Casseus (Detective Mendez), Wole Damarola (Greenlaw), Kyana Teresa (Lanaia), Nina Iordanova (Bartender)
- Written By: Zoe Broad
- Directed By: Salli Richardson-Whitfield
- Ep: 48
- To the Night Children
- Guest Starring: David Castro (Raphael Santiago), Tessa Mossey (Heidi McKenzie), Luke Baines (Jonathan Morgenstern), Steve Byers (Underhill), Alex Mallari, Jr. (Detective Greere), Romaine Waite (Griffin), Conrad Coates (Detective Dwyer), Jacky Lai (Aline)
- Co-Starring: Ayisha Issa (Annaliese), Aimee Bessada (Elle), Katie Strain (Nora), Josh Horvath (Joshua), Valerie Boyle (Elderly Woman), Rosie Simon (Nurse), Massey Ahmar (Guard)
- Written By: Peter Binswanger
- Directed By: Siluck Saysanasy
- Ep: 49
- Stay With Me
- Guest Starring: Javier Muñoz (Lorenzo Rey), Luke Baines (Jonathan Morgenstern), Anna Hopkins (Lilith), Nicola Correia-Damude (Maryse Lightwood), Lola Flanery (Seelie Queen), Jade Hassouné (Meliorn), Pasha Ebrahimi (Cain), Kimberly-Sue Murray (Adult Seelie Queen), James McGowan (Praetor Scott)
- Co-Starring: Sophia Walker (Catarina), Kyana Teresa (Lanaia)
- Written By: Aisha Porter-Christie
- Directed By: Amanda Row
- Ep: 50
- Guest Starring:
- Co-Starring:
- Written By:
- Directed By:
- Ep: 51
- Guest Starring:
- Co-Starring:
- Written By:
- Directed By:
- Ep: 52
- Guest Starring:
- Co-Starring:
- Written By:
- Directed By:
- Ep: 53
- Guest Starring:
- Co-Starring:
- Written By:
- Directed By:
| Katherine McNamara .................... Clary Fray |
| Dominic Sherwood .................... Jace Wayland |
| Alberto Rosende ...................... Simon Lewis |
| Matthew Daddario .................. Alec Lightwood |
| Emeraude Toubia ............... Isabelle Lightwood |
| Alisha Wainwright ................... Maia Roberts |
| Isaiah Mustafa ..................... Luke Garroway |
| Harry Shum, Jr. ...................... Magnus Bane |
