Dan thinks everyone and everything is out to get him.
He could be right.
Season One: 22 episodes
| Ep | PN | Airdate | Title |
| 1 | | Jan 01/11 | Dan vs. New Mexico |
| 2 | | Jan 01/11 | Dan vs. The Wolf-Man |
| 3 | | Jan 08/11 | Dan vs. The Dentist |
| 4 | | Jan 15/11 | Dan vs. The Ninja |
| 5 | | Jan 22/11 | Dan vs. The Animal Shelter |
| 6 | | Jan 29/11 | Dan vs. Canada |
| 7 | | Feb 26/11 | Dan vs. Traffic |
| 8 | | Mar 05/11 | Dan vs. Ye Olde Shakespeare Dinner Theatre |
| 9 | | Mar 12/11 | Dan vs. Baseball |
| 10 | | Mar 19/11 | Dan vs. The Salvation Armed Forces |
| 11 | | Mar 26/11 | Dan vs. The Beach |
| 12 | | Apr 02/11 | Dan vs. George Washington |
| 13 | | Apr 09/11 | Dan vs. Technology |
| 14 | | Apr 16/11 | Dan vs. The Barber |
| 15 | | Apr 30/11 | Dan vs. Art |
| 16 | | May 14/11 | Dan vs. Elise's Parents |
| 17 | | May 21/11 | Dan vs. The Fancy Restaurant |
| 18 | | May 28/11 | Dan vs. Dan |
| 19 | | Jun 04/11 | Dan vs. The Family Camping Trip |
| 20 | | Jun 18/11 | Dan vs. Burgerphile |
| 21 | | Jun 25/11 | Dan vs. The Magician |
| 22 | | Jul 09/11 | Dan vs. The Lemonade Stand Gang |
Season Two: 18 episodes
| Ep | PN | Airdate | Title |
| 23 | | Nov 19/11 | Dan vs. The Family Thanksgiving |
| 24 | | Dec 17/11 | Dan vs. The Mall Santa |
| 25 | | Jan 28/12 | Dan vs. The Neighbors |
| 26 | | Feb 04/12 | Dan vs. Dancing |
| 27 | | Feb 11/12 | Dan vs. The Bank |
| 28 | | Feb 18/12 | Dan vs. The Monster Under the Bed |
| 29 | | Feb 25/12 | Dan vs. Golf |
| 30 | | Mar 03/12 | Dan vs. The Gym |
| 31 | | Mar 24/12 | Dan vs. The Wedding |
| 32 | | Mar 31/12 | Dan vs. The Catburglar |
| 33 | | Apr 07/12 | Dan vs. The Dinosaur |
| 34 | | Apr 14/12 | Dan vs. Stupidity |
| 35 | | May 19/12 | Dan vs. The Telemarketer |
| 36 | | May 26/12 | Dan vs. Reality TV |
| 37 | | Jun 02/12 | Dan vs. Parents |
| 38 | | Jun 09/12 | Dan vs. Gigundo-Mart |
| 39 | | Jun 16/12 | Dan vs. Chris |
| 40 | | Jun 23/12 | Dan vs. Wild West Town |
Season Three: 14 episodes
| Ep | PN | Airdate | Title |
| 41 | | Nov 17/12 | Dan vs. Anger Management |
| 42 | | Nov 24/12 | Dan vs. The Mummy |
| 43 | | Dec 01/12 | Dan vs. The Boss |
| 44 | | Dec 08/12 | Dan vs. The Mechanic |
| 45 | | Dec 15/12 | Dan vs. The High School Reunion |
| 46 | | Jan 19/13 | Dan vs. The Common Cold |
| 47 | | Jan 26/13 | Dan vs. The DMV |
| 48 | | Feb 02/13 | Dan vs. The Ski Trip |
| 49 | | Feb 09/13 | Dan vs. Jury Duty |
| 50 | | Feb 16/13 | Dan vs. Vegetables |
| 51 | | Feb 23/13 | Dan vs. The Superhero |
| 52 | | Mar 02/13 | Dan vs. The Family Cruise |
| 53 | | Mar 09/13 | Dan vs. Summer Camp |