Guest Starring: Michael O'Keefe (Philip Gifford), Diane Venora (Lea Muller), Marc Blucas (Detective McNeill), Jimmi Simpson (Will Sanders), Lindsay Pulsipher (Kelly Frost), Damien Leake (Dr. Hayward), Matt O'Leary (Bobby)
And: Kate Nelligan (Gepetto)
Co-Starring: Ryan William Lee (David), Kavita Patil (Lab Manager), Romy J. Park (Gifford's Assistant), Leslie Ishi (Female Doctor), Shirley Jordan (Nurse), Virginia Montero (Elderly Woman), Michael Osborne (Young Guy #1), Joe Hendrix (Forensic #1)
Teleplay By: Mick Davis
Directed By: Danny Cannon
Ep: 2
Cardiac
Guest Starring: Erica Gimpel (Lizzie Summers), Jessica Hecht (Mrs. Beatrice Brown), Sam Hennings (Deputy Sheriff Bill Larsson), Zach Mills (Stephen Brown), Daniel Roebuck (Principal Craig), Henry G. Sanders (Sam Tewsbury)
Co-Starring: Christy Oldham (Anna Freeman), Tate Berney (Calum Freeman), Jarrod Bailey (Daniel Harker), Reid Harper (Freddy St. John), Joey Luthman (Jesse Freeman), Edmund Wyson (Mr. Harker), Kelley Hazen (Mrs. Harker), Rick Cramer (Neal St. John), Steven Walsh, Jr. (Randy), Brown Zach Mills (Stephen), Chip Hormess (Wallace), Kirk Bovill (Concerned Father), Angela Hughes (Concerned Mother), Regina Hoyles (Kid in Audience), Nicole Butler (Lab Tech)
Written By: Mick Davis
Directed By: Clark Johnson
Ep: 3
Agro
Guest Starring: R. Lee Ermey (Bob Henson), Scott Lawrence (Wallace Bennett), Angus Macfadyen (Jason Cooper), Dawn Stern (Dr. Lisa Richards), Joel Bissonnette (Karl Altschuler), Haley Ramm (Emily Stanner)
Co-Starring: Leith Burke (Agent Morris), Jeremy Denzlinger (Ed Henson), Alexandra Raines (Mrs. Stanner), Robb Reesman (Agent Wilson), Alex Wexo (Sam Sheridan), Cinda Adams (Vicky Henson), Tina Battaglia (Reporter), Adrian Colon (Cop), Stephen Hale (Biochem Geek), Tim Haldeman (Crane Operator), Jeff Howard (EMT #1), Sean Hampton (EMT #2), Jose Rosario (Foreman), Obren Milanovic (Resident)
Written By: Heather Mitchell
Directed By: Danny Cannon
Ep: 4
Savant
Guest Starring: Stephen Bogardus (Dr. Edward Fisher / Man at Microscope), Valerie Dillman (Storybook Mom), Stacy Edwards (Miss Catherine Bonatelli), Sahara Garey (Teresa Kimsey), Megan Paul (Elizabeth), Kim Staunton (Mrs. Kimsey), Keith Szarabajka (Agent Whittier)
Co-Starring: David Hiller (Cameron Stewart), Mark Doerr (Mr. Butler / Distraught Man), Brandon Salgado (Noah Fisher), David Lewis (Scott Butler), Rusty Burns (Concerned Lady), Charles Carroll (Coroner), Elaine Kao (Hospital Orderly), Justin Dray (Orderly), Jimm Giannini (Security Guard), Michael Gambino (Uniform #1), Brian Jones (Uniforrm #2)
Written By: Ildy Modrovich
Directed By: Terry McDonough
Ep: 5
Containment
Guest Starring: John Cassini (Alan Pulido), Scott Connors (Dale Walsh), Oded Fehr (Calvert Rigdon), Henri Lubatti (Ned Warner)
Co-Starring: Allyson Ryan (Cathy Warner), Noland Gould (Johnny Warner), Carlos Moreno, Jr. (Manny), Catherine Kresge (Lab Tech), Albert Garcia (Police Officer), Mark Berry (Scientist), Michael Wyle (Skeletal Body), Noelle Adames (Translator), Lazarus Jackson (Worker)
Written By: Adam Targum
Directed By: Danny Cannon
Ep: 6
Frozen
Guest Starring: Paul Fitzgerald (Lucas Nash), John Getz (William Gregory), Marisol Ramirez (Detective Carla Cordero), Scott Allen Rinker (Edward Grekowski), Roma Chugani (Elizabeth Ramesh), Jackie Ngan (Janet Lin)
Co-Starring: Melanie Hawkins (Emily Grekowski), Joel Bryant (Joey Lux), Jonna Walsh (Marlena Gower), Lisa Tharps (Doctor), Robert Patteri (Owner), Adrian Quinonez (Paramedic), Kai Schmoll (Professor), Kody Corduan (Surfer)
Written By: Andre Bormanis
Directed By: Karen Gaviola
Ep: 7
Surge
Guest Starring: Will Estes (Kevin Pierce), Scoot McNairy (Rudy Callistro), Judd Nelson (Dr. Bruce Nesic), Patrick St. Esprit (Henry Brooks)
Co-Starring: Lorena Segura York (Abby Pierce), Timothey Fitzgerald (Agent Reed), Andrew T. Lee (Howard Kim), Griffin Cleveland (Jackson Pierce), Manny Montana (Vasquez), Brian Elerding (Dealer #1), Dennis Kiefer (Dealer #2), Tanner Gill (Deputy), Matthew Jones (Paramedic), Eda Darvish (Pathologist)
Teleplay By: Angel Dean Lopez
Story By: Fred Golan
Directed By: Guy Ferland
Ep: 8
Titans
Guest Starring: Patrick Carroll (Dylan Petraneck), Meagen Fay (Dr. Bridget Ruscillo), Nic Few (Lawrence Richmond), Torri Higginson (Alex), Dennis Hill (Isaac Richmond), Alex Nesic (Ellis Brockton), Erik Palladino (Blake Miller), Lindsey Shaw (Vivian Bingham)
Co-Starring: Ossie Mair (Dr. Cogan), Lauren Champey (Tara Bingham), Patric Knutsson (Wade Earlham), Jared Gilmore (Owen), Philip Shahbaz (ER Doctor), Kevin C. Carter (FAA Engineer), Jules Bruff (Flight Attendant), Sean Gentry (Petty Officer)
Written By: Speed Weed
Directed By: Nick Gomez
Ep: 9
Flesh
Guest Starring: Christina Chang (Professor Anna Yang), Scott Klace (Dr. Henry West), Sam Murphy (Derek Kenin), Michael Grant Terry (Lenny Reese), Sandra Thigpen (Dr. Audrey Simone)
Co-Starring: Slade Wiggins (Belinda Shea Laura), Meg Marie Cionni (Kayla Perry), Kathleen Mary Carthy (Sally Tyler), Danny Weaver (Seth Sandel), Robin Thomas (Dr. Tom Carraway), Christie Ann Burson (Tabitha Jackson), Paul Ganus (Mr. Jackson), Annie Larussa (Mrs. Jackson), John Everlove (EMT #1), Raquel Bell (EMT #2), Sandra Vergara (Hot Co-Ed), John Sterling Carter (Medical Examiner), Raquel Gardner (Newscaster #1), Juan M. Fernandez (Newscaster #2)
Written By: Ben Lee
Directed By: David M. Barrett
Ep: 10
H2O
Guest Starring: Dave Florek (Larry Driggs), Paul Rae (Leon / DWP Worker), Blake Shields (Greg Filmore), Pat Skipper (Gill Strickland), Liza Weil (Ashley Filmore)
Co-Starring: Mario Cortez (Captain Joseph Lorigo), Toni Torres (Rosario Martinez), Ian Plant (Troy Filmore), Marco Morales (Danny), Jay Caputo (Javier), T. Ryan Mooney (Marco), Jeannie Epper (Mrs. Friedman), Renee Santos (Checkout Girl), Christopher David Carlisle (Concierge), Tyler Vogt (Hipster), John O'Brien (Manager), Janora McDuffie (Uni)
Teleplay By: Heather Mitchell
Story By: Kim Newton
Directed By: Terry McDonough
Ep: 11
Miracle
Guest Starring: Jo Anderson (Helen Cole), Myndy Crist (Dr. Veronica Reeves), Angela Gots (Lily Kessler), Gattlin Griffith (Nicky Harris), Raphael Sbarge (Dr. Matthew Kaplan), Bob Stephenson (Daniel Harris), Gideon Emery (Brandon Hertle), Brad Greenquist (Travis Dobbs)
Co-Starring: Matthew Alan (Ben Adams), Rene Hamilton (Child Protective Services), Jack Forbes (Detective), Derrick McMillon (Hazmat Worker), Blaine Capatch (Hydrologist), Zach Lewis (Local Cop), Erica Shaffer (Reporter on TV), Craig Tsuyumine (Reporter #1), Justin Hibbard (Reporter #2), Kinga Philipps (Reporter #3), Stephen Ramsey (Sergeant), Tom Virtue (Surgeon)
Teleplay By: Mick Davis
Based on the UK episode Written By: Simon Stephenson
Directed By: Paul Shapiro
Ep: 12
Eternal
Guest Starring: Nina Dobrev (Grace Dahl), Christopher Fields (Dr. Bruce Templeton), Ivana Milicevic (Isabelle Van Dyke), Bruce Thomas (Dr. Niles Davison), Jake Thomas (Brian Dahl), Kim Thomson (Devin), Chandra West (Angie Parks)
Co-Starring: Paul Perri (Richard Dahl), Nicole Pulliam (Assistant), Angel Desai (Endocrinologist), Tim Pulice (M.E.), Phillipe Simon (Maitre D'), Erica Freene (Receptionist / Young Woman), Joe Gerety (Superintendant), Holly Reiser (Willowy Blonde)
Written By: Ildy Modrovich
Directed By: Jeffrey Hunt
Ep: 13
Pinocchio
Guest Starring: Kevin Alejandro (ICE Agent Ray de la Pea), Tom Costello (Dave Price), Vanessa Martinez (Neli Gamarro), Michael McGrady (Val Tambor), Debra Mooney (Pete Hammer), Jorge-Luis Pallo (Cristofer)
Guest Starring: Omar Benson Miller (FBI Agent Felix Lee), Michael Cudlitz (Ben Finney), Kevin Linehan (Terry Gillman), Ion Overman (Debbie Baylor), Eric Pierpoint (Joseph Breen), Susan May Pratt (Erica Gillman), Bernard White (Dr. Travis Nayar)
Co-Starring: Ben Shields (Walter Barrett), Cari Champion (Anchorwoman), Ric Sarabia (Junk Man), John Murray (RV Guy)
Written By: Adam Targum
Directed By: Dermott Downs
Ep: 15
Electro
Guest Starring: Omar Benson Miller (FBI Agent Felix Lee), Mina Badie (Marty Jeffries), Taylor Nichols (Rebecca Wease), Molly Price (Dr. Elias Lowenthal), John Prosky (Chase Coleman), Jamison Yang (Dr. Elizabeth Hansen), Michael Peter Bolus (ER Doctor)
Co-Starring: Jackie Kreisler (Candi Cayne), Jonathan Goldstein (Charlie Wease), Dana May Salah (Denise Hall), Rob Chester Smith (Dickie), Jamie Burton-Oare (Field Tech), Bon Ogle (Hippie Employee), Jeris Lee Poindexter (Security Guard)
Teleplay By: Heather Mitchell
Story By: Andre Bormanis
Directed By: Nick Gomez
Ep: 16
Subway
Guest Starring: Omar Benson Miller (FBI Agent Felix Lee), Juan Garcia (), John Lafayette (Clark Ashton), Julian Morris (Quinn)
And: Mariel Hemingway (Mary Jo)
Co-Starring: Marcia Ann Burrs (Bernadette Wilson), Christie Lynne Smith (Fran Lieber), Elizabeth Tripp (Amy), Tanner Maguire (Darren), Rico E. Anderson (Dave), Gina Rodriguez (Robin), Lee Burns (EMT), Kendra Danielle Smith (ER Nurse), Stefanie Black (Triage Nurse)
Written By: Stephen Gallagher
Directed By: Paul McCrane
Ep: 17
Olfactus
Guest Starring: Omar Benson Miller (FBI Agent Felix Lee), Bree Condon (Hailey Vaughn), Valerie Cruz (Coco Delgado), Caitlin Dulany (Diane Randal), Rizwan Manji (Tony), Esteban Powell (Renny Boyle), John Shea (Kristopher Merced), Samantha Shelton (Gretchen Morris), Tehmina Sunny (Lyla)
