• Guest Starring: Geoff Pierson (Mystery Man), Michael Dorn (Dr. Carver Burke), Victor Webster (Josh Davidson), Scott Paulin (Jim Beckett), John M. Jackson (Rod Halstead), Larry Anderson (Dr. Kovaks), Valerie Azlynn (Uniform)
• Co-Starring: Joshua Dov (Dale Landers), Landon Ashworth (Mitch Yancey), Azure Parsons (Ginny), Roger Narayan (ER Resident), Paris Tanaka (ER Nurse), Ruben Dario (EMT)
• Written By: Andrew W. Marlowe
• Directed By: Rob Bowman

• Guest Starring: Valerie Azlynn (Ann Hastings), Kenneth Mitchell (Paul Whittaker), Hank Harris (Chad Hockney), Jamie McShane (Tony "The Butcher" Valtini), Eric Tiede (Mike Hoover), Maura Soden (Mrs. Faris), Michelle Van Der Water (Marie Marcado)
• Co-Starring: James Ferris (Tyler Faris), Maxine Hayden (Old Lady)
• Written By: David Amann
• Directed By: Jeff Bleckner

• Guest Starring: William Atherton (Dr. Ari Weiss), Shaun Toub (Dr. Philip Boyd), Judith Hoag (Cynthia Hamilton), Jordan Belfi (Beau Randolph), Andy Umberger (Johnny Rosen), Jared Hillman (Eddie Peck), Susan Grace (Carla)
• Co-Starring: Christopher Goodman (Man #1), Keith Lal (Man #2), Tiffany Panhilason (Monica)
• Written By: David Grae
• Directed By: Holly Dale

• Guest Starring: Ross McCall (Seth Carver), Tim Jo (Ben Lee), Billy Lush (Finn McQueen), Francois Chau (Clifford Lee), Lanny Joon (Philip Lee), Mercedes Colon (Philip Lee's Attorney), Nadine Crocker (Jane Herzfeld's Roommate), Stephanie Nash (Annika Herzfeld)
• Co-Starring: Joe Martin Thomas (Bodyguard), Sam Ayers (Bartender), Michael Yavnieli (Marshall Drooen)
• Written By: Moira Kirland
• Directed By: Rob Bowman

• Guest Starring: Kristin Lehman (Serena Kaye), Jessica Tuck (Joy McHugh), David Hunt (Falco), Michael Dorn (Dr. Carter Burke), Aasha Davis (Alyssa Lofters), Jessica Lundy (Myrna Ramsey), James Read (Anton McHugh), Benjamin Ciaramello (Finn)
• Co-Starring: Carolyn Ratteray (Waitress)
• Written By: Shalisha Francis
• Directed By: John Terlesky

• Guest Starring: Frederic Lehne (Addison Smith), Amanda Walsh (Jack's Producer), Vernée Watson (Mercy LaGrande), Mark Harelik (Pete Benton), Juliana Dever (Jenny Duffy-O'Malley), Vincent Guastaferro (Steve Fuller), Joel Stoffer (Ron Berger), Shawn Carter Peterson (Barry Bavetta)
• Co-Starring:
• Written By: Rob Hanning
• Directed By: Bill Roe

• Guest Starring: Dean Norris (Captain Peterson), Darren Pettie (Trapper John), Ian Kahn (Ron Brandt), Jack Laufer (Davenport the Bank Manager)
• Co-Starring: Ty Upshaw (Dr. Huxtable), Noa Dori (Dr. Quinn), Jonah Wharton (Dr. Howser), Dawn-Lyen Gardner (Simone Jenkins), Barry Livingston (Abe), Aimee Parker (Grace), Frank Birney (Father McCaskey), Matt Medrano (Officer Monfriez), Tatum Shank (Officer Billups), Holly Daniels (Tanya Brandt), Quinn Friedman (Connor)
• Written By: Terence Paul Winter
• Directed By: Bryan Spicer

• Guest Starring: Richard Burgi (Charlie Turner), Eric Ladin (Daniel Sullivan), Laura Regan (Rebecca Siegal), Jeffrey Vincent Parise (Tom Moretti), David Figlioli (Ralph Marino), Ashley Wood (Amber Lively)
• Co-Starring: Susie Castillo (Nadine Espinoza), Jennifer Del Rosario (Juliette Chang), Ben Seaward (Jeremy), Markus Silbiger (Brian), Nathalie Walker (Hot Showgirl)
• Written By: Elizabeth Davis
• Directed By: Bill Roe

• Guest Starring: Michael Dorn (Psychiatrist Carter Burke), Scott Michael Campbell (Lee Travis), Troy Winbush (Marcus Ford), Mandy June Turpin (Lee's Sister), Tony Elias (Chris Nunez), Karissa Vacker (Emily Reese)
• Co-Starring: Christina Ferraro (Sarah Vasquez), Alexis Carra (Julie), Joe Regullano (Anna), Natalie Lander (Marie), Marc Istook (Newscaster #1), Diane Mizota (Newscaster #2), Adam Pilver (Manager), Marcus Choi (EMT), Mark Nelson (Hot Shot)
• Written By: Alexi Hawley
• Directed By: David M. Barrett

• Guest Starring: Darin Heames (Agent Chuck Martinez)
• Co-Starring: Deborah Van Valkenburgh (Ruth Spurloch), Brett Wagner (Jack Spurloch), Brad Carter (Bobby Spurloch), Brian Jones (State Trooper McNichols)
• Written By: Terri Edda Miller & Andrew W. Marlowe
• Directed By: John Terlesky

• Guest Starring: Jaime Ray Newman (Holly Franklin), Sam Hennings (Seth Harris), Juliana Dever (Jenny Duffy-O'Malley), Mo Mandel (Max), Desmin Borges (Pablo), Jenna Gering (Lisa Hill)
• Co-Starring: Parisa Fakhri (Colette Roth), Brian D. Johnson (Ron Hill), Donald Agnelli (Barry), Donna Feldman (Jody Lopez), Timon Kyle Durrett (Toby Lang), Crystal Coney (Judy Doyle), Tammy Felice (Sexy Woman #1), Kristina Geddes (Sexy Woman #2), Byrne Offutt (Manager), Lindsay LaVanchy (Assistant), Haley Strode (Hot Young Woman), Daniel Romer (Cute Young Guy)
• Written By: David Grae
• Directed By: Jeff Bleckner

• Guest Starring: Geoff Pierson (Mystery Man), Derek Webster (Mayor Robert Weldon), Adam Kulbersh (Brian Shay), Michael Grant Terry (Jordan Norris), Rebecca Field (Marilyn Kane), Germaine De Leon (Edgar Navarro), Steven Brand (Trevor Haynes), Cara Pifko (Roberta Cambridge), Dave Florek (Harvey), Victoria Platt (Connie Park), Mimi Michaels (Sarah Marx)
• Co-Starring: Patrick Cohen (Patrick McConnell), D.C. Douglas (Bill Moss), Susan Spano (Kitty), Tracy Scoggins (Lana), Tara Platt (Janelle), Cecelia Specht (Screaming D.A.G. Operator)
• Written By: Christine Boylan
• Directed By: Kate Woods

• Guest Starring: Hilarie Burton (Kay Cappuccio), Justin Hartley (Reggie Starr), Nana Visitor (Dr. Patty Barker), Kevin E. West (Teddy Wiser / Jack Patterson), Tommy Savas (Marcus Hiatt), Scott Lowell (David Hernand), Jim Abele (Adam Green)
• Co-Starring: Tiffany Lowery (Phoebe), Ed F. Martin (Francisco Pilar), Dale Waddington (Kelly Gunther), Robin Sachs (Announcer), Charles Carpenter (Reporter), Andre Ing (Photographer), Diane Modafferi (Uniform Cop)
• Written By: Rob Hanning
• Directed By: Thomas J. Wright

• Guest Starring: Mark Pellegrino (Tom Dempsey), Chad Everett (Jerry Maddox), Ellen Geer (Viola Maddox), Patrick Cassidy (Clyde Belasco), Zahn McClarnon (Ray Horton), Lorin McCraley (Westside Wally), Andrea Grano (Mrs. Banks)
• Co-Starring: Adam Bay (Leonard), Sarah Lilly (Luella McManus), Darin Toonder (Frankie), Jared Ward (Bartender)
• Written By: Terrence Paul Winter
• Directed By: Chuck Bowman

• Special Guest Star: Jennifer Beals (Sophia Turner)
• Guest Starring: Josh Stamberg (Martin Danberg), David Chisum (Thomas Gage), Timothy Carhart (Dr. Blakely), Julia Whelan (Tina Massey), Bruno Oliver (Scientist)
• Co-Starring: Russell Edge (Jones), Dave Shalansky (Tech #1), Burnadean Jones (Tech #2)
• Written By: David Amann
• Directed By: Bryan Spicer

• Special Guest Star: Jennifer Beals (Sophia Turner)
• Guest Starring: Josh Stamberg (Martin Danberg), David Chisum (Thomas Gage), Jim Turner (Janacek Spivey), Cal Gibson (Chess Player)
• Co-Starring: Russell Edge (Jones), Burnadean Jones (Tech #2), Lak Rana (Tech #3), Jade Carter (Agent Jack Corrigan), David Lim (Agent Trahn), Steve Kramer (Super)
• Written By: Andrew W. Marlowe
• Directed By: Rob Bowman

• Guest Starring: Meghan Markle (Charlotte Boyd), Taylor Kinney (Darren Morgan), Sarah Jane Morris (Leslie Morgan), June Squibb (Jamie Isaacson), Jason Thompson (Noah Curtis), Gloria Garayua (Jesse)
• Co-Starring: Nicholas Downs (Marcus O'Neill), Lindsey Santefort (Amy Morgan / Red Riding Hood)
• Written By: Kate Sargeant
• Directed By: Jeff Bleckner

• Guest Starring: Adam Harrington (Brad Melville), Tim Ransom (Max Renfro), Larry Sullivan (Samuel Lynchberg), Millicent Martin (Oona Marconi), Mike Faiola (Paul Morton), Bruce Gray (Charles Carson), Neil Brown, Jr. (Eddie Gordon), Arlene Santana (Jasmine), Matthew Alan (Jason Bagwell), Shelli Boone (Chantel), Erin Chambers (Suzanne Steiner)
• Co-Starring: Lauralee Bell (Pam Francis), Braeden Marcott (Pierre Dubois), Krishna Cole (Santino), Anna Lunberry (Jeanine), Karla Mosley (P.A.)
• Written By: Moira Kirland
• Directed By: Kevin Hooks

• Guest Starring: Christine Woods (Leann West), Tim Guinee (Andrew Haynes), Walter Perez (Bobby Lopez), Matthew Carey (Mr. Levine)
• Co-Starring: Michael Rose (Agent Johnson), Samuel Child (Jesse Friedman), Gilbert Owuor (Malik), Lorin McCraley (West Side Wally), Nikki Novak (Corinne), Ann Reilly (Val Brookstone), John Ruby (Mark), Kate Siegel (Nadia), Michael Alperin (Beethoven), Wil Bowers (Male Reporter), David C. Scott (Host)
• Written By: Shalisha Francis
• Directed By: Paul Holahan

• Guest Starring: Brett Tucker (Simon Hunt), Charles Shaugnessy (Nigel Winthrop), Omar J. Dorsey (Biggie Slim), Danielle Bisutti (Claire Panchard), Chrystee Pharris (Nicky Jay)
• Co-Starring: Matthew Brenher (Bryson), Keith Chandler (Tech), Joe Coots (Morgan), Tiffany Jeneen (Motel Maid)
• Written By: Elizabeth Davis
• Directed By: Bill Roe

• Guest Starring: Adam Baldwin (Detective Ethan Slaughter), Michael Dorn (Dr. Carter Burke), Michael McGrady (Brian Reilly), Rey Gallegos (Vales), Anna Zielinski (M.E. Laura Wilson)
• Co-Starring: Christopher Rivera (Detective Marc Gibson), Clifford McGhee (Maxi), Mario Ardila, Jr. (Gilberto Mendoza), Stefan Niemczyk (Shea), Ramona DuBarry (Reporter), Jan M. Janssen (Officer Jenkins), Carter Mitchell (Homeless Man)
• Written By: Alexi Hawley
• Directed By: John Terlesky

• Guest Starring: Arye Gross (M.E. Perlmutter), Ryan Doom (Tom Williams), Tiffany Dupont (Greta Mastroianni), Josh Braaten (Kyle Jennings), Brandon Keener (Charlie Coleman), Kevin Symons (Mike Matthews)
• Co-Starring: Kevin Sheridan (Paul), Maxwell Glick (Rhett), Ross Kurt Le (Aleem), Amaris Davidson (Jen)
• Written By: Christine Boylan
• Directed By: Bill Roe

• Guest Starring: Tahmoh Penikett (Cole Maddox), Geoff Pierson (Mystery Man), Judith Scott (Evelyn Montgomery), Onahoua Rodriguez (Marisol Cartagena), Lobo Sebastian (Diego Gutierrez), Sal Lopez (Priest)
• Co-Starring: Riccardo LeBron (Orlando Costas)
• Written By: Terri Edda Miller & Andrew W. Marlowe
• Directed By: Rob Bowman