Starring: Jeffrey Hunter (Captain Christopher Pike)
Guest Star: Susan Oliver (Vina)
Co-Starring: Leonard Nimoy (Mister Spock), Majel Barrett (Number One), John Hoyt (Doctor Boyce), Peter Duryea (Lieutenant Tyler), Laurel Goodwin (Yeoman Colt)
Uncredited: Meg Wylie (The Keeper)
Written By: Gene Roddenberry
Directed By: Robert Butler
Ep: 1
The Man Trap
Co-Starring: Jeanne Bal (Nancy Crater)
Guest Star: Alfred Ryder (Professor Robert Crater)
Featuring: DeForest Kelley (Dr. McCoy), Grace Lee Whitney (Yeoman Janice Rand), George Takei (Sulu), Nichelle Nichols (Uhura), Bruce Watson (Green), Michael Zaslow (Darnell), Vince Howard (Crewman), Francine Pyne (Nancy III)
Written By: George Clayton Johnson
Directed By: Marc Daniels
Ep: 2
Charlie X
Guest Star: Robert Walker (Charlie Evans)
Featuring: DeForest Kelley (Dr. McCoy), Grace Lee Whitney (Yeoman Rand), Nichelle Nichols (Uhura), Charles J. Stewart (Captain Ramart), Dallas Mitchell (Nellis), Don Eitner (Navigator), Patricia McNulty (Tina Lawton), John Bellah (Crewman I), Garland Thompson (Crewman II), Abraham Sofaer (The Thasian)
Story By: Gene Roddenberry
Teleplay By: D. C. Fontana
Directed By: Lawrence Dobkin
Ep: 3
Where No Man Has Gone Before
Guest Stars: Gary Lockwood (Lieutenant Commander Gary Mitchell), Sally Kellerman (Dr. Elizabeth Dehner)
Featuring: George Takei (Sulu), James Doohan (Scott), Lloyd Haynes (Alden), Andrea Dromm (Yeoman Smith), Paul Carr (Lieutenant Lee Kelso), Paul Fix (Doctor Piper)
Written By: Samuel A. Peeples
Directed By: James Goldstone
Ep: 4
The Naked Time
Co-Starring: Stewart Moss (Tormolen), Majel Barrett (Christine), Bruce Hyde (Riley)
Featuring: DeForest Kelley (Dr. McCoy), Grace Lee Whitney (Yeoman Rand), George Takei (Sulu), James Doohan (Scott), Nichelle Nichols (Uhura), William Knight (Amorous Crewman), John Bellah (Laughing Crewman)
Written By: John D. F. Black
Directed By: Marc Daniels
Ep: 5
The Enemy Within
Featuring: DeForest Kelley (Dr. McCoy), Grace Lee Whitney (Yeoman Rand), George Takei (Sulu), James Doohan (Scott), Edward Madden (Fisher), Garland Thompson (Wilson), Jim Goodwin (Farrell)
Written By: Richard Matheson
Directed By: Leo Penn
Ep: 6
Mudd's Women
Guest Star: Roger C. Carmel (Harry Mudd)
Co-Starring: Karen Steele (Eve)
Featuring: DeForest Kelley (Dr. McCoy), Maggie Thrett (Ruth), Susan Denberg (Magda), James Doohan (Scott), George Takei (Sulu), Jim Goodwin (Farrell), Nichelle Nichols (Uhura), Gene Dynarski (Ben), Jon Kowal (Herm), Seamon Glass (Benton), Jerry Foxworth (Guard)
Guest Stars: Kim Darby (Miri), Michael J. Pollard (Jahn)
Featuring: DeForest Kelley (Dr. McCoy), Grace Lee Whitney (Yeoman Rand), Keith Taylor (Jahn's Friend), Ed McCready (Boy Creature), Kellie Flanagan (Blonde Girl), Steven McEveety (Redheaded Boy), David Ross (Security Guard #1), Jim Goodwin (Farrell), John Megna (Little Boy)
Written By: Adrian Spies
Directed By: Vincent McEveety
Ep: 9
Dagger of the Mind
Guest Star: James Gregory (Dr. Tristan Adams)
Co-Starring: DeForest Kelley (Dr. McCoy), Morgan Woodward (Dr. Simon Van Gelder), Marianna Hill (Helen Noel)
Featuring: Nichelle Nichols (Uhura), Susanne Wasson (Lethe), John Arndt (First Crewman), Larry Anthony (Transportation Man), Ed McCready (Inmate), Eli Behar (Therapist)
Written By: S. Bar-David
Directed By: Vincent McEveety
Ep: 10
The Corbomite Manoever
Co-Starring: Anthony Call (Dave Bailey), Clint Howard (Balok)
Featuring: DeForest Kelley (Dr. McCoy), Grace Lee Whitney (Yeoman Rand), George Takei (Sulu), James Doohan (Scott), Nichelle Nichols (Uhura)
Written By: Jerry Sohl
Directed By: Joseph Sargent
Ep: 11
The Menagerie
Special Guest Star: Jeffrey Hunter (Captain Christopher Pike)
Guest Star: Susan Oliver (Vina)
Also Starring: Malachi Throne (Commodore Mendez), M. Leigh Hudec (Number One), Peter Duryea (Lieutenant Tyler), John Hoyt (Doctor Boyce), Adam Roarke (CPO Garrison), DeForest Kelley (Dr. McCoy), James Doohan (Scott), Nichelle Nichols (Uhura)
Special Guest Star: Jeffrey Hunter (Captain Christopher Pike)
Guest Star: Susan Oliver (Vina)
Also Starring: Malachi Throne (Commodore Mendez), M. Leigh Hudec (Number One), Peter Duryea (Lieutenant Tyler), John Hoyt (Doctor Boyce), Laurel Goodwin (Yeoman Colt), Adam Roarke (CPO Garrison), DeForest Kelley (Dr. McCoy), James Doohan (Scott), Nichelle Nichols (Uhura)
Featuring: Sean Kenney (Disabled Captain Pike), Hagan Beggs (Ensign Hansen), Meg Wylie (The Keeper)
Written By: Gene Roddenberry
Directed By: Robert Butler
Ep: 13
The Conscience of the King
Guest Star: Arnold Moss (Karidian)
Also Starring: Barbara Anderson (Lenore)
Featuring: DeForest Kelley (Dr. McCoy), Grace Lee Whitney (Yeoman Rand), Nichelle Nichols (Uhura), William Sargent (Dr. Leighton), Natalie Norwick (Martha Leighton), David-Troy (Larry Matson), Karl Bruck (King Duncan), Marc Adams (Hamlet), Bruce Hyde (Kevin Riley)
Written By: Barry Trivers
Directed By: Gerd Oswald
Ep: 14
Balance of Terror
Also Starring: Mark Lenard (Romulan Commander)
Co-Starring: Paul Comi (Stiles), Lawrence Montaigne (Decius)
Featuring: DeForest Kelley (Dr. McCoy), Grace Lee Whitney (Yeoman Rand), George Takei (Sulu), James Doohan (Scott), Nichelle Nichols (Uhura), Stephen Mines (Tomlinson), Barbara Baldavin (Angela), Garry Walberg (Hansen), John Warburton (The Centurion)
Written By: Paul Schneider
Directed By: Vincent McEveety
Ep: 15
Shore Leave
Co-Starring: Emily Banks (Tonia Barrows), Oliver McGowan (Caretaker), Perry Lopez (Rodriguez)
Featuring: DeForest Kelley (Dr. McCoy), George Takei (Sulu), Bruce Mars (Finnegan), Barbara Baldavin (Angela), Nichelle Nichols (Uhura), Marcia Brown (Alice), Sebastian Tom (Warrior), Shirley Bonne (Ruth)
Written By: Theodore Sturgeon
Directed By: Robert Sparr
Ep: 16
The Galileo Seven
Co-Starring: Don Marshall (Boma), DeForest Kelley (Dr. McCoy), James Doohan (Scott)
Featuring: George Takei (Sulu), Nichelle Nichols (Uhura), John Crawford (Commissioner Ferris), Peter Marko (Gaetano), Phyllis Douglas (Yeoman Mears)
With: Rees Vaughn (Latimer), Grant Woods (Kelowitz), Buck Maffei (Creature), David Ross (Transporter Chief)
Story By: Oliver Crawford
Teleplay By: Oliver Crawford & S. Bar-David
Directed By: Robert Gist
Ep: 17
The Squire of Gothos
Guest Star: William Campbell (Trelane)
Featuring: DeForest Kelley (Dr. McCoy), Richard Carlyle (Jaeger), Nichelle Nichols (Uhura), George Takei (Sulu), James Doohan (Scott), Michael Barrier (DeSalle), Venita Wolf (Teresa)
Written By: Paul Schneider
Directed By: Don McDougall
Ep: 18
Arena
Guest Stars: DeForest Kelley (Dr. McCoy), George Takei (Sulu), James Doohan (Scott), Nichelle Nichols (Uhura), Jerry Ayres (O'Herlihy), Grant Woods (Kelowitz), Tom Troupe (Lieutenant Harold), James Farley (Lang), Carole Shelyne (Metron), Sean Kenney (DePaul)
Story By: Fredric Brown
Teleplay By: Gene L. Coon
Directed By: Joseph Pevney
Ep: 19
Tomorrow is Yesterday
Also Starring: Roger Perry (Major Chistopher)
Featuring: DeForest Kelley (Dr. McCoy), Hal Lynch (Air Police Sergeant), Richard Merrifield (Technician), John Winston (Transporter Chief), Ed Peck (Colonel Fellini)
With: James Doohan (Scott), George Takei (Sulu), Nichelle Nichols (Uhura), Mark Dempsey (Air Force Captain), Jim Spencer (Air Policeman), Sherri Townsend (Crew Woman)
Featuring: Brioni Farrell (Tula), Sid Haig (First Lawgiver), Charles Macaulay (Landru), Jon Lormer (Tamar), Morgan Farley (Hacom), Christopher Held (Lindstorm)
With: George Takei (Sulu), James Doohan (Scott), Nichelle Nichols (Uhura), Sean Morgan (O'Neil), Ralph Maurer (Bilar), David L. Ross (Guard)
Featuring: Barbara Babcock (Mea 3), Miko Mayama (Tamula), David L. Ross (Galloway), Nichelle Nichols (Uhura), Sean Kenney (DePaul), Robert Sampson (Sar 6)
Special Guest Star: Frank Overton (Elias Sandoval)
Featuring: Grant Woods (Kelowitz), George Takei (Sulu), Nichelle Nichols (Uhura), Michael Barrier (DeSalle), Dick Scotter (Painter), Eddie Paskey (Crewman)
Story By: Nathan Butler & D.C. Fontana
Teleplay By: D. C. Fontana
Directed By: Ralph Senensky
Ep: 25
The Devil in the Dark
Guest Stars: DeForest Kelley (Dr. McCoy), Ken Lynch (Vanderberg)
Featuring: James Doohan (Scott), Brad Weston (Appel), Biff Elliot (Schmitter), George E. Allen (Engineer #1), Jon Cavett (Guard), Barry Russo (Giotto)
Written By: Gene L. Coon
Directed By: Joseph Pevney
Ep: 26
Errand of Mercy
Guest Stars: John Abbott (Ayelborne), John Colicos (Kor)
Featuring: George Takei (Sulu), Nichelle Nichols (Uhura), Peter Brocco (Claymare), Victor Lundin (Lieutenant), David Hillary Hughes (Trefayne), Walt Davis (Klingon Soldier), George Sawaya (Second Soldier)
With: Nichelle Nichols (Uhura), Richard Derr (Barstow), Arch Whiting (Assistant Engineer), Christian Patrick (Transporter Chief), Eddie Paskey (Lesley)
Written By: Don Ingalls
Directed By: Gerd Oswald
Ep: 28
The City on the Edge of Forever
Guest Star: Joan Collins (Sister Edith Keeler)
Also Starring: DeForest Kelley (Dr. McCoy)
Featuring: James Doohan (Scott), George Takei (Sulu), Nichelle Nichols (Uhura), John Harmon (Rodent), Hal Baylor (Policeman), David L. Ross (Galloway), John Winston (Transporter Chief), Bartell La Rue (Guardian Voice)
Written By: Harlan Ellison
Directed By: Joseph Pevney
Ep: 29
Operation--Annihilate!
Guest Star: DeForest Kelley (Dr. McCoy)
Featuring: James Doohan (Scott), Joan Swift (Aurelan), Maurishka (Yeoman Zahra), Majel Barrett (Christine Chapel)
With: George Takei (Sulu), Nichelle Nichols (Uhura), Craig Hundley (Peter), Fred Carson (First Denevan), Jerry Catron (Second Denevan)